UDK: 616.89-008.454:616-073.756.8

THE VOXEL-BASED MORPHOMETRY AND DIFFUSION-TENSOR IMAGING METHODS IN DIAGNOSTICS OF DEPRESSIVE DISORDERS

E. Y. Abritalin

Военно-медицинская академия имени С. М. Кирова, Санкт-Петербург

Abstract

32 depressive patients were investigated using several neuroimaging methods. Functional and structural abnormalities were established in limbic structures in all groups of patients. Almost all of these structures are parts of so-called frontal sub-cortical circuits. The structural neural imaging results (voxel-based morphometry, diffusion-tensor imaging) revealed tracts deficiency in fornix, callous corpus and cingilate convolutions. Observed similar changes (for patients with different depression types) can be a neural biological substrate of depression syndrome of different genesis, and identified differences may indicate that depression can be caused by various pathological processes.

Keywords

depressive disorders, voxel-based morphometry, diffusion-tensor imaging

Contacts

Абриталин Евгений Юрьевич — к. м. н., докторант при кафедре психиатрии Военно-медицинской академии им. С. М. Кирова, е-mail: abritalin@rambler.ru