Journal of VolgSMU
Quarterly scientific-practical journal

UDK: 616.36-002:615.244

EFFECT OF SODIUM HYPOCHLORITE THERAPY ON LIPID PEROXIDATION, ANTIOXIDANT PROTECTION, CYTOLYTIC AND MESENCHIMAL-INFLAMMATORY SYNDROMES IN PATIENTS WITH TOXIC HEPATITIS

D. N. Yemelyanov, R. G. Miazin

Кафедра пропедевтики внутренних болезней ВолгГМУ

Abstract

106 patients with toxic hepatitis were treated with the infusion course of sodium hypochlorite as monotherapy. Levels of lipid peroxidation, antioxidative enzymes activity, cytolytic and mesenchimal-inflammatory syndrome were determined before and after therapy course. Treatment revealed valuable positive dynamics of all indexes, improvement of the general status of patients after therapy. Thus, treatment with sodium hypochlorite is a new effective medicamentous method in patients with toxic hepatitis.

Keywords

sodium hypochlorite, lipid peroxidation, antioxidant protection, cytolytic syndrome, mesenchimal-inflammatory syndrome, toxic hepatitis

Contacts

Мязин Роман Геннадиевич – к. м. н., ассистент кафедры пропедевтики внутренних болезней Волгоградского государственного медицинского университета, e-mail: naclo@mail.ru