UDK: УДК 615.22:616.12-005.4:616.24-036.12-085.22

IIVABRADINE, VERAPAMIL SR OR AMLODIPINE EFFICACY IN TREATMENT OF CORONARY HEART DISEASE PATIENTS WITH CONCOMITANT ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE EXACERBATIONS

A. N. Podolskaya, O. V. Magnitskaya

Кафедра клинической фармакологии и интенсивной терапии ВолгГМУ

Abstract

Open-label parallel group randomized investigation was performed. Ivabradine (15 mg/day), verapamil SR or amlodipine were administered for treatment of postMI silent ischemic patients with stable angina and concomitant chronic obstructive pulmonary disease (COPD) or asthma exacerbations. All drugs showed equal antianginal and antiischemic activity. They did not aggravate respiratory function or clinical symptoms of concomitant asthma and COPD. All drugs were well tolerated.

Keywords

coronary heart disease (CHD), chronic obstructive pulmonary disease (COPD), asthma, exacerbation, ivabradine, verapamil, amlodipine.

Contacts

Магницкая Ольга Валерьевна — д. м. н., профессор кафедры клинической фармакологии и интенсивной терапии с курсами клинической фармакологии ФУВ ВолгГМУ, e-mail: magol73@yandex.ru