Journal of VolgSMU
Quarterly scientific-practical journal

UDK: 615.3:797.2+612.13

THE FEATURES OF PHENIBUTUM INFLUENCE ON PARAMETERS OF BLOOD SYSTEM CIRCULATION AND MECHANISM FORMATION FOR MAINTAINING BLOOD PRESSURE

1ФГБОУ ВО «Волгоградский государственный медицинский университет», 2ФГБОУ ВО «Волгоградская государственная академия физической культуры», 3ФГБОУ ВО «Волгоградский государственный университет»

Abstract

The article presents the results of studying the features of phenibutum influence on parameters of blood system circulation and formation of mechanisms for maintaining blood pressure of swimmers aged 10—12 years with disadaptation symptoms and to the information received. For measuring and recording of hemodynamic parameters the tetrapolar rheography method was used. It is shown that a number of age-specific cardiovascular system characteristics in the control group and in the group of placebo were significantly less represented in the literature. At the same time the pumping function of heart in these groups was determined mainly by heart activity and slightly — vascular component. Between TPR and: pump, notropic function of heart and myocardial contractility and capacity of the left ventricle (respectively) revealed significant negative relationship, which indicated that the predominant role of the heart and small — of the vascular component in the maintenance of blood pressure. At the same time as the disadaptated swimmers who took phenibutum the heart pumping indicators were normalized. This occurred to a greater extent due to the significant increase in the contribution of inotropic component in maintaining blood pressure. The correlation analysis makes possible come to conclusion that the pumping function of heart at the same time kept largely cardiac output, myocardial contractility, heart rate capacity. A significant contribution to the maintenance of optimal blood pressure has brought the capacity of left ventricle. Between the peripheral vascular resistance and: pumping function of heart,myocardial was found negative relationship.

Keywords

phenibutum, systemic hemodynamic, disadaptated swimmers, recovery.

Contacts

Лиходеева Вера Александровна — д. б. н., доцент каф. анатомии и физиологии ВГАФК, e-mail: v-lihodeeva@mail.ru