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EFFECTS OF PERCHLOZON AND ANTIBODIES AGAINST HUMAN GAMMA-INTERFERON AND CD4 GLYCOPROTEIN ON THE IMMUNE SYSTEM OF HIV-INFECTED PATIENTS WITH ASSOCIATED PULMONARY TUBERCULOSIS

A. V. Strygin, A. S. Klyausov, A. M. Dotsenko, A. O. Strygina, E. I. Morkovin

Волгоградский государственный медицинский университет, Волгоградский медицинский научный центр

Abstract

This article presents the results of a study performed to estimate the effects of combined therapy with Perchlozon and antibodies against human CD4 and gamma-interferon in patients with HIV and pulmonary tuberculosis during the antiretroviral therapy. Perchlozon and antibodies against human CD4 and gamma-interferon combined with antiretroviral therapy were found to increase the number of CD4+ cells and IL-4 concentrations in blood plasma, which could have a good prognostic value for treatment of patients with HIV and lung tuberculosis co-infection.

Keywords

HIV, pulmonary tuberculosis, co-infection, Perchlozon, antiretroviral therapy, antibodies against human CD4 and gamma-interferon.

Contacts

Стрыгин Андрей Валерьевич — к. м. н., зав. кафедрой фундаментальной медицины и биологии, Волгоградский государственный медицинский университет, e-mail: drumsav@mail.ru