UDK: 615.014.2
A.A. Spasov, V.A. Kosolapov
ФГБОУ ВО «Волгоградский государственный медицинский университет» Министерства здравоохранения Российской Федерации
The article discusses the development of drugs using technology of pharmaceutical alternatives. One of the possible directions is the synthesis, investigation and implementation of the new salts, esters or complexes of original drugs. Examples of the introduction of drugs, which are the pharmaceutical alternatives to previously registered drugs, are amlodipine maleate, clopidogrel besylate, mexidol, perindopril arginine salt, and others. This makes the development of drugs using alternative salts of the same component perspective by creating new drugs, with special attention is required to study the bioequivalence and therapeutic equivalence of newly developed salts.
generic drug, pharmaceutical alternatives, pharmaceutical equivalents.
Спасов Александр Алексеевич – академик РАН, заслуженный деятель науки РФ, д. м. н., профессор, заведующий кафедрой фармакологии и биоинформатики, Волгоградский государственный медицинский университет, e-mail: aspasov@mail.ru