UDK: 612.017.3:616-056.43
A.A. Panina1, E.B. Belan2, I.G. Shushkova3, E.D. Lutaya1
ФГБОУ ВО «Волгоградский государственный медицинский университет» Министерства здравоохранения Российской Федерации, Волгоград, 1кафедра лучевой,
The standard methods of the specific diagnosis of respiratory allergy were compared. 233 patients with allergic diseases were examined. Serum level of the specific IgE has been measured by in vitro methods in exacerbation of the disease (n = 686), skin tests have been carried out in the remission according to a standard procedure (n = 203). The techniques with manually with disk reagents (108 patients, n = 340) and automatic Immulite analyzer (125 patients, n = 346) have been used in the first case. The validity of the differences between the compared groups was assessed by analyzing the conjugacy tables and calculating the statistical criterion hi-square (X2). Statistically valid differences in the frequency of sensitization to cat epithelium/hair, meadow and weed allergens, alpha-and beta-lactoglobulins as the result of comparing of manual and automatic methods of the measurement of the level of specific IgE haven’t been revealed. The frequency of the confirmation of the results by skin tests was 92,6, 88,3 and 87,8 % for cat's epithelium/hair, meadow and weed allergens, respectively. Serum level of specific IgE to pollen allergens didn’t correlate with size of wheal in skin testing. Conclusion. Thus, manual and automatic methods are comparable for the specific diagnosis of respiratory allergy. The possibility of the choice of an allergen for the specific immunotherapy independently on level of IgE it’s necessary to study.
allergodiagnostics, specific IgE.
Панина Анна Александровна – к. м. н., доцент кафедры лучевой, функциональной и лабораторной диагностики ИНМФО ВолгГМУ, e-mail: panina_volg@rambler.ru