UDK: 618.11-006.6

DEFINING RISK DEGREE OF OVARIAN CANCER RECURRENCES USING MORPHOMETRICAL AND IMMUNOHISTOCHEMICAL RESEARCH OF A PRIMARY TUMOR

Ye. V. Novichkov

Кировская государственная медицинская академия

Abstract

Quantimetrical and immunohistichemical characteristics of ovarian cancer with high risk of relapse compared with ovarian carcinoma without recurrences were studied on operative and biopsy material from 120 patients. It was established that serous ovarian carcinoma with high risk of tumor relapse had a lesser cellular size, but a higher nuclear-cellular ratio. Morphometrical criteria of early cancer relapse (up to 6 months) and late recurrences of tumor growth were detected. Immunohistochemical parameters (mt p53, PCNA) allow a reliable prediction of relapse of serous ovarian cancer.

Keywords

ovarian cancer, recurrent tumor, morphometry, immunohistochemical analysis

Contacts

Новичков Евгений Владимирович — кандидат медицинских наук, доцент кафедры патологической анатомии Кировской государственной медицинской академии, e-mail: novichkovjenya@mail.ru