UDK: 616.12-008.331.1:615.225.2

Renin-angiotensin-aldosteron system block: comparison of the results of combined therapy with cardostan in combination with enalapril and with diovan in combination with enalapril in patients with the first degree arterial hypertension in combination with

E. V. Frolova

Кафедра клинической фармакологии и интенсивной терапии ВолГМУ

Abstract

System metabolic effects of combined therapy by cardostan with enalapril in comparison with diovan and enalapril combination were studied. 50 patients with the first degree arterial hypertension in combination with metabolic syndrome were selected. The combined therapy by cardostan with enalapril or diovan with enalapril was administered. In 24 weeks hypotensive effect of both combinations was the same and it allows to achieve targeted blood pressure, but favorable effect on lipid profile was influenced by the combination of cardostan and enalapril. The unfavorable effect on serum creatinine index was revealed in combined use of diovan and enalapril.

Keywords

renin-angiotensin-aldosteron system, treatment, cardostan, enalapril, diovan, metabolic syndrome

Contacts

Фролова Екатерина Викторовна — заместитель главного врача по медицинской части клиники семейной медицины ВолГМУ, e-mail: e.v.frolova@mail.ru