UDK: 612.112.94:612.017:616-006

THE STATE OF METABOLIC STATUS OF LYMPHOCYTES IN THE BLOOD OF PATIENTS WITH ACUTE ALYMPHOBLASTIC LEUKEMIA

O. V. Smirnova, V. T. Manchuk, A. A. Savchenko

Научно-исследовательский институт медицинских проблем Севера, Красноярск

Abstract

We examined the activity of metabolic enzymes of lymphocytes in 100 pts with acute alymphoblastic leukemia (variant M4). Pts with acute alymphoblastic leukemia in all stages of the disease had changes of the activity of metabolic enzymes of lymphocytes. The most important changes of the activity of metabolic enzymes of lymphocytes in pts with acute alymphoblastic leukemia were revealed during recurrence. The revealed immunological and metabolic disturbances depending on the stage of acute alymphoblastic leukemia characterize immunopathogenetic aspects in the development and progress of acute alymphoblastic leukemia.

Keywords

metabolic enzymes of lymphocytes, acute alymphoblastic leukemia

Contacts

Смирнова Ольга Валентиновна — к. м. н., с. н.с. лаборатории молекулярно-клеточной физиологии и патологии ГУ НИИ медицинских проблем Севера СО РАМН, e-mail: ovsmirnova71@mail.ru