UDK: 616.12-008.331.1+ 616-005.4]-092
M. V. Pokrovskiy, V. I. Kochkarov, T. G. Pokrovskaia, E. B. Artiushkova, E. N. Pashin, L. M. Danilenko, M. V. Korokin, A. S. Belous, V. A. Malyhin
Курский государственный медицинский университет
The modelling of deficiency of oxide nitrogen introduction L-NAME to rats led to development of arterial hypertension, increase in the factor of endothelial dysfunction, decrease in the maintenance of nitrates/nitrites levels, hypertrophy of cardiomyocytes. Introduction of donors NO, activators of No-sintase, antioxidants, antihypertensive drugs has revealed comparable endotelioprotective effects.
oxide nitrogen, L-NAME, endothelial dysfunction
Покровский Михаил Владимирович — д. м. н., профессор, зав. кафедрой фармакологии Курского государственного медицинского университета, e-mail: mvpokrovskiy@pharmstd.ru